same state
partial overlap
marker high
marker low
contested (≠)
transition
not linked to a state
blue year = our papers
Since 1985, SCLC has been split into classic/variant, NE/non-NE, A/N/P/Y, A/N/P/I, archetypes, clusters and NMF groups. Each box is a label from one paper. Lines show which of the current states (colored circles) it corresponds to, only where the paper itself supports the link: a double line means the same state, a single line means partial overlap; dashed boxes are not linked. Click anything for details, including what kind of data (human tumors, cell lines, mouse models, organoids) each state was found in. For example, ISL1 is high in SCLC-A and low in SCLC-A2 (Wooten 2019), and the later "ISL1+ subtype" (Shields 2026) overlaps SCLC-A.
Each row is a paper; each column is a current state. Bold = same state; gray italic = partial overlap.